Case Nº 026 · Dr. Irina Turchin

EC2Change Case FileAtopic dermatitis

A 41-year-old female with severe disease

Special sites: hands

At a glanceCase Nº 026

At a glance

A 41-year-old female, severe atopic dermatitis

Score	Baseline	Latest visit
EASI	4	0
Itch NRS	10	0
IGA	4	0
DLQI	19	0

In this file

The patientCase Nº 026

The patient

year-old female,
severe disease

Special-site involvement

Special sites involved: Hands

Previous diagnoses

41 yo woman with severe chronic hand dermatitis and mild atopic dermatitis

Comorbidities & context

Asthma

Treatment historyCase Nº 026

Treatment history

What came before

Treatment at presentation

tralokinumab

Previous topical therapy

High potency topical steroids, tacrolimus, topical antibiotics

Previous systemic therapy

Prednisone x multiple courses Oral antibiotics

Disease assessmentCase Nº 026

Disease assessment

Severity at baseline

EASI

Eczema Area and Severity Index

4of 72

Itch NRS

Peak pruritus numerical rating scale

10of 10

IGA

Investigator's Global Assessment

4of 4

DLQI

Dermatology Life Quality Index

19of 30

Disease assessmentCase Nº 026

Disease assessment

On the skin

Erythema

Red / pink

Disease assessmentCase Nº 026

Disease assessment

How it shaped care

Other impact

severe hand disease

Disease assessmentCase Nº 026

Baseline photographs

Disease assessmentCase Nº 026

Baseline photographs

Treatment selectionCase Nº 026

Treatment selection

The plan

Tralokinumab

Treatment goals

Clear hands

Follow-upCase Nº 026

Follow-up · visit 1 of 1

12 months or more on treatment

12 mo

EASI

Eczema Area and Severity Index

0of 72

−4 vs baseline of 4

BSA

Body surface area

0%of 100%

Itch NRS

Peak pruritus numerical rating scale

0of 10

−10 vs baseline of 10

IGA

Investigator's Global Assessment

0of 4

−4 vs baseline of 4

DLQI

Dermatology Life Quality Index

0of 30

−19 vs baseline of 19

Follow-upCase Nº 026

Follow-up · visit 1 of 1

Visit 1, continued

Lesions at this visit

Erythema: — None
Thickness: — None
Lichenification: — None
Other: — Clear

Treatment plan

Treatment continued unchanged

Patient satisfied
Physician satisfied

Follow-upCase Nº 026

Visit 1 photographs

OutcomesCase Nº 026

Outcomes

Scores over time

V = follow-up visit. Each scale starts at zero.

A 41-year-old female with severe atopic dermatitis.

EC2Change Case File Nº 026

Contributed by Dr. Irina Turchin. Compiled from the physician’s case-builder submission, in their own words.